Poznan is an important centre for the automotive, food, pharmaceutical, chemical and machine industry. The leading producers on a national scale include: Volkswagen Poznan Sp. z o. o., Bridgestone Poland Sp. z o. o., Exide Technologies SA, Kompania Piwowarska SA , Unilever Polska Sp. z o.o., Wrigley Poland Sp. z o. o., Wyborowa SA, Jutrzenka Colian Sp. z o.o. Zaklad w Poznaniu, Uniq Lisner Sp. z o. o., Terravita Sp. z o. o., Poznańska Palarnia Kawy Astra® Sp. z o. o., Spoldzielnia Piekarsko-Ciastkarska "Fawor," GlaxoSmithKline Pharmaceuticals SA, Nivea Polska Sp. z o. o., Przedsiebiorstwo Farmaceutyczne "Ziololek" Sp. z o. o., Poznanskie Zaklady Farmaceutyczne "Herbapol" SA, Grupa Kapitalowa H. Cegielski - Poznan SA, SKF Poznan SA.

Industry is a source of income for 35% of the total number of people employed in Poznan in the enterprises sector, and it delivers, the second to services, largest part of gross value added generated in the city. The main share of total sales revenue in the industry in Poznan is held by: the production of food products and beverages (22%), the generation and supply of electrical energy, gas, hot water and steam (10%), and the manufacture of rubber and plastic products (7 %). The structure of sold production of industry and employment in the enterprises sector indicates the growing importance of high-tech sectors in industrial production. The largest high-tech manufacturing companies of Poznan are: Exide Technologies SA, Fabryka Wodomierzy Powogaz SA, GlaxoSmithKline Pharmaceuticals SA, Grupa H. Cegielski SA, Kreisel - Technika Budowlana Sp. z o.o., Nivea Polska SA, Poznanskie Zaklady Zielarskie Herbapol SA, SKF Poznan SA, Volkswagen Poznan Sp. z o.o., Wytwornia Sprzetu Komunikacyjnego - Poznan Sp. z o.o.